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Thinning of tracheal mucosa was more severe in females (Fig

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Further, while the suppression of urge to smoke appeared comparable between the 1.6 % and the 2.4 % test formulations in the present study, evaluation of the mean puff counts and the amount of solution consumed did not suggest that the subjects compensated by puffing on the lower-nicotine products consciously or subconsciously more so than the higher-nicotine products to achieve a similar level of satisfaction